Fig. 3
From: Trans-activation-based risk assessment of BRCA1 BRCT variants with unknown clinical significance
Effect of post-transfection incubation times on TA assay sensitivity. Comparison of the TA activity for selected variants after 24- (dark green) and 48 (light green)-h post-transfection incubation time. a HEK293T cells. b MDA-MB-231. TA activity is displayed as the percentage of wt trans-activation activity. Error bars represent standard deviations (n ≥ 18) for three to four experiments (*p value < 0.001)