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Fig. 3 | Human Genomics

Fig. 3

From: A novel knowledge-derived data potentizing method revealed unique liver cancer-associated genetic variants

Fig. 3

Heat map of SNP variant impacts. a SNP with frameshift Insertion (SIFT score 0.00–1). b SNP with frameshift deletion (SIFT score 0.00–1). Worse functional impact SIFT score ranges from 0.00 represents a deleterious effect in genes to 1 represents tolerated effect in genes. SIFT score ranges from 0.00 (deleterious) to 1.0 (tolerated). Variants with scores closer to 0.00 are more confidently predicted to be deleterious. Variants with scores 0.05 to 1 are predicted to be tolerated (benign). Variants with scores very close to 1 are more confidently predicted to be tolerated. Horizontal axis represents the gene order distance

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Human Genomics

ISSN: 1479-7364