Fig. 2
From: Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes
Regional plot of association results at 22q13 in MM alongside recombination rates and histone marks in GM12878. Plot shows discovery association results of both genotyped and imputed SNPs in the GWAS samples and recombination rates. −log10 P values (y axes) of the SNPs are shown according to their chromosomal positions (x axes). The colour of each symbol reflects the extent of LD with the top genotyped SNP. Genetic recombination rates, estimated using HapMap samples from Utah residents of western and northern European ancestry (CEU), are shown with a blue line. Physical positions are based on NCBI build 37 of the human genome. Also shown are the relative positions of GENCODE v19 genes mapping to the region of association. Below the association plot are the relative positions of GENCODE v19 genes mapping to the region of association and the histone marks and chromatin loops for lymphoblastoid cell line, GM12878