Table 6 Stratified analyses of the rs2151280 with lung cancer risks and NSCLC by smoking

Never

TT

172 (36.1)

121 (41.7)

1.00 (ref)

87 (39.7)

1.00 (ref)

TC

229 (48.1)

138 (47.6)

0.857 (0.626–1.173)

0.334

0.865 (0.624–1.201)

0.387

107 (48.9)

0.924 (0.654–1.305)

0.653

0.954 (0.665–1.368)

0.798

CC

75 (15.8)

31 (10.7)

0.588 (0.364–0.948)

0.029

0.518 (0.316–0.851)

0.009

25 (11.4)

0.659 (0.391–1.109)

0.117

0.572 (0.334–0.980)

0.042

0.790 (0.586–1.066)

0.123

0.773 (0.567–1.056)

0.106

0.858 (0.618–1.193)

0.363

0.850 (0.604–1.197)

0.351

0.640 (0.409–1.000)

0.050

0.561 (0.354–0.891)

0.014

0.689 (0.425–1.118)

0.131

0.587 (0.356–0.968)

0.037

T allele

573 (60.2)

380 (65.5)

1.00 (ref)

281 (64.2)

1.00 (ref)

C allele

379 (39.8)

200 (34.5)

0.796 (0.642–0.986)

0.037

157 (35.8)

0.845 (0.668–1.068)

0.158

ever

TT

31 (47.0)

86 (39.6)

1.00 (ref)

66 (37.9)

1.00 (ref)

TC

26 (39.4)

106 (48.8)

1.470 (0.812–2.661)

0.204

1.477 (0.762–2.862)

0.248

89 (51.1)

1.608 (0.873–2.961)

0.128

1.812 (0.894–3.673)

0.099

CC

9 (13.6)

25 (11.5)

1.001 (0.421–2.379)

0.998

0.992 (0.378–2.608)

0.987

19 (10.9)

0.992 (0.403–2.440)

0.985

1.025 (0.366–2.872)

0.962

1.349 (0.775–2.349)

0.290

1.351 (0.728–2.508)

0.340

1.449 (0.818–2.569)

0.204

1.599 (0.826–3.094)

0.164

0.825 (0.364–1.867)

0.644

0.815 (0.328–2.027)

0.660

0.776 (0.332–1.815)

0.559

0.756 (0.287–1.987)

0.570

T allele

88 (66.7)

278 (64.1)

1.00 (ref)

221 (63.5)

1.00 (ref)

C allele

44 (33.3)

156 (35.9)

1.122 (0.744–1.694)

0.583

127 (36.5)

1.149 (0.753–1.754)

0.518