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Table 6 Stratified analyses of the rs2151280 with lung cancer risks and NSCLC by smoking

From: Association between polymorphism in CDKN2B-AS1 gene and its interaction with smoking on the risk of lung cancer in a Chinese population

GenotypingLung cancer Non-small-cell lung cancer 
 Controls (%)Cases (%)OR (95%CI)P valueORª (95%CI)Pª valueCases (%)OR (95%CI)P valueORª (95%CI)Pª value
Never           
TT172 (36.1)121 (41.7)1.00 (ref)   87 (39.7)1.00 (ref)   
TC229 (48.1)138 (47.6)0.857 (0.626–1.173)0.3340.865 (0.624–1.201)0.387107 (48.9)0.924 (0.654–1.305)0.6530.954 (0.665–1.368)0.798
CC75 (15.8)31 (10.7)0.588 (0.364–0.948)0.0290.518 (0.316–0.851)0.00925 (11.4)0.659 (0.391–1.109)0.1170.572 (0.334–0.980)0.042
CC+TC vs TT 0.790 (0.586–1.066)0.1230.773 (0.567–1.056)0.106 0.858 (0.618–1.193)0.3630.850 (0.604–1.197)0.351
CC vs TC+TT 0.640 (0.409–1.000)0.0500.561 (0.354–0.891)0.014 0.689 (0.425–1.118)0.1310.587 (0.356–0.968)0.037
T allele573 (60.2)380 (65.5)1.00 (ref)   281 (64.2)1.00 (ref)   
C allele379 (39.8)200 (34.5)0.796 (0.642–0.986)0.037  157 (35.8)0.845 (0.668–1.068)0.158  
ever           
TT31 (47.0)86 (39.6)1.00 (ref)   66 (37.9)1.00 (ref)   
TC26 (39.4)106 (48.8)1.470 (0.812–2.661)0.2041.477 (0.762–2.862)0.24889 (51.1)1.608 (0.873–2.961)0.1281.812 (0.894–3.673)0.099
CC9 (13.6)25 (11.5)1.001 (0.421–2.379)0.9980.992 (0.378–2.608)0.98719 (10.9)0.992 (0.403–2.440)0.9851.025 (0.366–2.872)0.962
CC+TC vs TT 1.349 (0.775–2.349)0.2901.351 (0.728–2.508)0.340 1.449 (0.818–2.569)0.2041.599 (0.826–3.094)0.164
CC vs TC+TT 0.825 (0.364–1.867)0.6440.815 (0.328–2.027)0.660 0.776 (0.332–1.815)0.5590.756 (0.287–1.987)0.570
T allele88 (66.7)278 (64.1)1.00 (ref)   221 (63.5)1.00 (ref)   
C allele44 (33.3)156 (35.9)1.122 (0.744–1.694)0.583  127 (36.5)1.149 (0.753–1.754)0.518  
  1. OR odds ratio, CI confidence interval, NSCLC non-small-cell lung cancer
  2. aAdjusted for age, gender, and smoking
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