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Table 1 Clinical profiles of patients with RIF and controls individuals

From: Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women

Characteristics

Controls

(n = 228)

RIF

(n = 118)

P value

Age (years)

33.8 ± 3.26

34.1 ± 3.21

0.296

BMI (kg/m2)

21.7 ± 3.31

21.0 ± 2.76

0.084

Previous implantation failure (n)

0

112

N/A

Live births (n)

1.77

0

N/A

Mean gestational age (weeks)

39.2 ± 1.69

0

N/A

PT (s)

11.3 ± 3.12

11.1 ± 1.49

0.0003†

aPTT (s)

30.8 ± 4.62

29.2 ± 3.42

0.024†

PLT (103/μl)

243.3 ± 59.99

233.9 ± 58.49

0.186

Homocysteine (μmol/L)

N/A

6.6 ± 1.34

N/A

Folate (mg/ml)

15.0 ± 8.97

15.6 ± 11.29

0.865

Total cholesterol (mg/dl)

229.4 ± 90.57

189.1 ± 44.68

0.062†

Uric acid (mg/dl)

N/A

3.9 ± 0.96

N/A

BUN (mg/dl)

8.1 ± 1.83

10.3 ± 2.82

< 0.0001†

Creatinine (mg/dl)

0.7 ± 0.08

0.8 ± 0.10

< 0.0001

E2 (Basal)

26.3 ± 14.72

2465.2 ± 2457.73

< 0.0001†

TSH (mU/L)

N/A

2.3 ± 1.43

N/A

FSH (mU/L)

8.2 ± 2.85

8.7 ± 4.52

0.784†

LH (mU/L)

3.3 ± 1.76

4.8 ± 2.29

< 0.0001†

Prolactin (ng/mL)

N/A

12.6 ± 6.21

N/A

WBC (103/μl)

N/A

7.2 ± 2.86

N/A

Hgb (g/dl)

N/A

12.6 ± 1.41

N/A

CD3 (pan T)

N/A

66.2 ± 11.28

N/A

CD4 (helper T)

N/A

33.9 ± 8.68

N/A

CD8 (suppressor)

N/A

29.0 ± 7.85

N/A

CD19 (B-cell)

N/A

11.0 ± 4.45

N/A

CD56 (NK cell)

N/A

20.0 ± 9.56

N/A

  1. Italicized text indicates significant P values. Data are presented as the mean ± standard deviation
  2. RIF, recurrent implantation failure; BMI, body mass index; PT, prothrombin time; aPTT, activated partial thromboplastin time; PLT, platelet count; BUN, blood urea nitrogen; E2, estradiol; TSH, thyroid stimulating hormone; FSH, follicle-stimulating hormone; LH, luteinizing hormone; WBC, white blood cell; Hgb, hemoglobin
  3. †Mann-Whitney test