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Table 4 Interaction analysis between recurrent implantation failure and coagulation factors in participants

From: Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women

  miR-25 rs1527423 T > C miR-32 rs7041716 C > A miR-125a rs12976445 C > T miR-222 rs34678647 G > T
PT (s) TT TC + TT CC CA + CC TT CT + TT TT GT + TT
 <12 1.000 (reference) 0.935 (0.526–1.665) 1.000 (reference) 1.433 (0.808–2.540) 1.000 (reference) 0.544 (0.295–1.005) 1.000 (reference) 1.135 (0.706–1.824)
 ≥12 7.560 (2.409–23.725) N/A 13.175 (3.745–46.350) N/A 5.946 (1.864–18.971) N/A 5.515 (1.056–28.792) 13.269 (2.823–62.379)
aPTT (s)
 <33.8 1.000 (reference) 1.022 (0.578–1.808) 1.000 (reference) 1.211 (0.678–2.161) 1.000 (reference) 0.547 (0.295–1.016) 1.000 (reference) 1.108 (0.693–1.771)
 ≥33.8 1.574 (0.659–3.760) 0.440 (0.050–3.865) 1.393 (0.598–3.245) 0.957 (0.085–10.779) 1.103 (0.415–2.931) 1.242 (0.339–4.558) 0.621 (0.193–1.998) 5.123 (1.379–19.030)
PLT (×103/μl)
 <294 1.000 (reference) 0.741 (0.391–1.403) 1.000 (reference) 1.081 (0.573–2.037) 1.000 (reference) 0.629 (0.340–1.163) 1.000 (reference) 1.386 (0.853–2.254)
 ≥294 0.832 (0.375–1.845) 1.641 (0.610–4.420) 0.999 (0.471–2.121) 1.512 (0.506–4.521) 1.167 (0.571–2.384) 0.616 (0.161–2.360) 1.397 (0.578–3.380) 1.114 (0.445–2.791)
  1. Italicized text indicates significant P values. The upper quartile for PT, aPTT, and PLT was 12 s, 33.8 s, and 294 × 103 platelets/μl respectively
  2. AOR, adjusted odds ratio; aPTT, activated partial thromboplastin time; PLT, platelet count; PT, prothrombin time
  3. Data are expressed as AOR (95% CI)