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Table 1 Demographic and clinical characteristics of the study cohort

From: Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms

n

HIV−non-smokers

HIV+non-smokers

HIV+tobacco smokers

p

40

60

25

 

Age (median [IQR])

58.5 [54.0, 64.0]

53.0 [45.8, 61.0]

49.0 [40.0, 55.0]

< 0.001

Race

   

0.001

 White

30 (75.0)

32 (53.3)

6 (24.0)

 

 Black

3 (7.5)

9 (15.0)

9 (36.0)

 

 Hispanic/Other

7 (17.5)

19 (31.7)

10 (40.0)

 

Education ≤ 12 years

1 (2.5)

8 (13.3)

6 (24.0)

0.021

Tobacco smoking

   

< 0.001

 Current

0 (0.0)

0 (0.0)

25 (100.0)

 

 Former

26 (65.0)

41 (68.3)

0 (0.0)

 

 Never

14 (35.0)

19 (31.7)

0 (0.0)

 

Marijuana smokinga

0 (0.0)

10 (16.7)

10 (40.0)

< 0.001

Alcohol usea

13 (32.5)

18 (30.0)

10 (40.0)

0.657

Cocaine usea

1 (2.5)

1 (1.7)

0 (0.0)

0.999

CES-D score

   

0.007

 0– < 16

33 (86.8)

44 (73.3)

12 (50.0)

 

 ≥ 16

5 (13.2)

16 (26.7)

12 (50.0)

 

BMI (kg/m2, median [IQR])

26.1 [22.9, 30.5]

25.2 [22.9, 27.8]

26.9 [22.3, 29.3]

0.630

HCV positive

0 (0.0)

1 (1.7)

1 (5.0)

0.368

HIV viral load (copies/ml, median [IQR])

––

10.0 [10.0, 10.0]

10.0 [10.0, 65.5]

0.093

HIV viral load ≤200 copies/ml

––

53 (91.4)

17 (85.0)

0.416

CD4 count (cells/μl, median [IQR])

915 [750, 1235]

598 [478, 854]

611 [318, 758]

< 0.001

  1. All data are n (%) unless otherwise indicated; p value denotes Fisher’s exact test, or Kruskal-Wallis rank sum test for continuous variables
  2. aDaily or weekly marijuana smoking, alcohol use, or cocaine use