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Fig. 3 | Human Genomics

Fig. 3

From: High heterogeneity undermines generalization of differential expression results in RNA-Seq analysis

Fig. 3

Evolution of detection power and union/intersection depending on the number of biological replicates. a–c The number of DEGs and the power of the intersection for a given number of biological replicates for each cancer type. d–f show the number of DEGs and the power of the union for a given number of biological replicates for each cancer type. For all the stacked bars in charts a–f, the blue part represents the number of DEGs that match with the corresponding referential intersection or union, while the orange part represents the specific DEGs (not match with the corresponding reference) of the intersection or union. Purple color bars in charts a–f represent the number of DEGs in the referential intersections or unions for each cancer type. g–i The number of DEGs in the union (green bar) and intersection (pink bar), as well as the union/intersection ratio (orange line), for a given number of biological replicates for each cancer type

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