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Table 4 Single marker association results for rs2288464 and rs9389268. Analyses of imputed FINRISK array data were performed with covariates for FINRISK genotyping batch. Bolded results are significant at the appropriate threshold for the given test (see Methods).

From: Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences

  FINRISK METSIM Joint analysis
Number MAF P Beta Number MAF P Beta Number MAF P Beta
rs2288464 Imputed 7927 0.148 0.613 0.0113 9791 0.165 2.55 × 10-9 0.119 17718 0.158 9.77 × 10-7 0.075
WES 9221 0.150 0.376 0.0186 9813 0.166 6.75 × 10-9 0.118 19034 0.158 9.34 × 10-7 0.0734
WGS 1084 0.142 0.383 0.0532 3065 0.161 0.113 0.0561 4149 0.156 0.0655 0.0562
rs9389268 Imputed 7927 0.354 0.189 0.0216 9791 0.347 1.26 × 10-10 0.0973 17718 0.35 1.62 × 10-8 0.0634
WGS 1084 0.351 0.788 0.0121 3065 0.347 3.24 × 10-8 0.150 4149 0.348 7.87 × 10-7 0.115