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Table 4 Single marker association results for rs2288464 and rs9389268. Analyses of imputed FINRISK array data were performed with covariates for FINRISK genotyping batch. Bolded results are significant at the appropriate threshold for the given test (see Methods).

From: Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences

 

FINRISK

METSIM

Joint analysis

Number

MAF

P

Beta

Number

MAF

P

Beta

Number

MAF

P

Beta

rs2288464

Imputed

7927

0.148

0.613

0.0113

9791

0.165

2.55 × 10-9

0.119

17718

0.158

9.77 × 10-7

0.075

WES

9221

0.150

0.376

0.0186

9813

0.166

6.75 × 10-9

0.118

19034

0.158

9.34 × 10-7

0.0734

WGS

1084

0.142

0.383

0.0532

3065

0.161

0.113

0.0561

4149

0.156

0.0655

0.0562

rs9389268

Imputed

7927

0.354

0.189

0.0216

9791

0.347

1.26 × 10-10

0.0973

17718

0.35

1.62 × 10-8

0.0634

WGS

1084

0.351

0.788

0.0121

3065

0.347

3.24 × 10-8

0.150

4149

0.348

7.87 × 10-7

0.115