Table 1 Principal component variance analysis (PCVA) decomposition of sources of variance
From: Altered splicing associated with the pathology of inflammatory bowel disease
| Â | Gene expression | PSI (108,091 exon bins) | PSI (7001 exon bins) |
|---|---|---|---|
Principal component | |||
  PC1 | 28.9% | 7.6% | 9.3% |
  PC2 | 25.1% | 5.5% | 6.9% |
  PC3 | 5.2% | 4.1% | 4.1% |
  PC4 | 4.4% | 3.0% | 3.2% |
  PC5 | 3.5% | 2.6% | 2.9% |
  PC6 | 2.3% | 2.4% | 2.7% |
  PC7 | 2.0% | 2.3% | 2.3% |
  PC8 | 1.6% | 1.8% | 2.0% |
  PC9 | 1.6% | 1.7% | 1.9% |
  PC10 | 1.3% | 1.7% | 1.6% |
  SUM of PC1–PC10 | 75.9% | 33.0% | 27.9% |
Variance component | |||
  Ancestry | 2.3% | 5.8% | 5.3% |
  Location | 0.2% | 0.7% | 0.5% |
  Disease | 40.3% | 20.7% | 27.9% |
  Location*disease | 0.8% | 0.8% | 1.0% |