Table 2 Description of the protein function effect classes of PGx variants, which are used as the training data for the final RF model. The functionality class is split in the following classes (“decreased,” “increased,” “no,” “normal”), the number of the respective PGx variants per class is also provided, as well as which pharmacogenes are incorporated per each class

From: A novel machine learning-based approach for the computational functional assessment of pharmacogenomic variants