Table 1 Parkinson's disease associated risk SNPs from an East Asian meta-genome-wide association study (Foo et al. [20])
From: Evaluation of low-pass genome sequencing in polygenic risk score calculation for Parkinson’s disease
rs ID | Chromosome | Position | Effect allele | Featurea | Effect allele frequency | |||
|---|---|---|---|---|---|---|---|---|
gnomAD v3.1 ALL | gnomAD v3.1 EAS | NARD ALL | NARD KOR | |||||
rs823118 | 1 | 205,723,572 | T | EUR replicated | 45.7% | 54.3% | 51.4% | 52.5% |
rs6679073 | 1 | 205,756,484 | A | EAS | 22.0% | 53.3% | 49.7% | 51.2% |
rs16846351 | 1 | 226,846,712 | G | EAS | 1.6% | 6.3% | 6.0% | 6.4% |
rs4653767 | 1 | 226,916,078 | T | EUR replicated | 72.7% | 72.1% | 23.8% | 22.2% |
rs2292056 | 3 | 182,735,211 | T | EAS | 77.9% | 41.5% | 59.9% | 63.1% |
rs12637471 | 3 | 182,762,437 | G | EUR replicated | 75.3% | 42.0% | 59.9% | 62.9% |
rs34311866 | 4 | 951,947 | C | EUR replicated | 14.2% | 13.8% | 17.7% | 16.9% |
rs11724635 | 4 | 15,737,101 | A | EUR replicated | 43.5% | 37.5% | 36.9% | 34.3% |
rs3816248 | 4 | 77,101,068 | T | EAS | 86.6% | 66.1% | 32.5% | 33.4% |
rs356182 | 4 | 90,626,111 | G | EUR replicated | 35.2% | 66.2% | 31.6% | 29.1% |
rs6826785 | 4 | 90,682,474 | C | EAS | 21.7% | 54.8% | 54.7% | 55.5% |
rs246814 | 5 | 75,599,208 | T | EAS | 9.6% | 9.1% | NA | NA |
rs1887316 | 6 | 112,151,452 | G | EAS | 81.1% | 87.9% | 12.4% | 14.2% |
rs997368 | 6 | 112,243,291 | A | EUR replicated | 65.5% | 64.2% | 39.3% | 39.6% |
rs9638616 | 7 | 70,750,493 | T | EAS | 37.9% | 49.2% | 55.0% | 55.1% |
rs12278023 | 11 | 83,510,117 | T | EAS | 55.1% | 50.2% | 47.7% | 48.6% |
rs3793947 | 11 | 83,544,472 | G | EUR replicated | 57.4% | 53.4% | 46.3% | 47.0% |
rs141336855 | 12 | 40,387,749 | T | EAS | 0.1% | 2.6% | 2.4% | 2.4% |
rs12456492 | 18 | 40,673,380 | G | EUR replicated | 32.8% | 38.0% | 42.7% | 40.9% |
rs4130047 | 18 | 40,678,235 | C | EAS | 32.2% | 37.8% | 42.6% | 40.7% |