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Table 1 Characteristics of the case/control cohort

From: Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci

Demographic Utah Iowa Combined cohort
N 3306 1481 4787
Age, median (IQR) 75.8 (13.2) 79.9 (11.1) 77.4 (12.7)
Males 1243 551 1794
Females 2057 930 2987
Controls    
N 1228 359 1587
Age, median (IQR) 71.6 (10.5) 77.8 (12.6) 72.8 (11.6)
Males 473 169 642
Females 755 190 945
Cases    
N 2078 1122 3200
Age, median (IQR) 78.8 (12.1) 80.4 (10.3) 79.45 (11.6)
Males 770 382 1152
Females 1302 740 2042
Early AMD 445 245 690 (11.7%)
Intermediate AMD 443 85 528 (10%)
Late AMD (atropy) 251 83 334 (10.4%)
Late AMD (neovascular) 852 666 1518 (47.4%)
Late AMD (atrophy and neovascular) 87 43 130 (4.1%)
Late AMD (combined) 1190 792 1982 (61.9%)