From shallow to deep: some lessons learned from application of machine learning for recognition of functional genomic elements in human genome

Table 2 Performance comparison for acceptor and donor site locations prediction; Se sensitivity, Sp specificity, Acc accuracy

Tool	Reference	Year	Signal type	Se	Sp	Acc
GeneSplicer	[24]	2001	Acceptor	69	97	83
GeneSplicer	[24]	2001	Donor	60	98	79
SplicePredictor	[25]	2004	Acceptor	84	92	88
SplicePredictor	[25]	2004	Donor	79	97	88
Zhang	[26]	2010	Acceptor	90	90
Zhang	[26]	2010	Donor	93	93
Bari	[27]	2012	Acceptor	77	89	89
Bari	[27]	2012	Donor	89	97	95
Goel	[23]	2015	Acceptor	94	94
Goel	[23]	2015	Donor	91	94
Wen	[29]	2017	Acceptor			93
Wen	[29]	2017	Donor			92
DeepSS	[30]	2018	Acceptor			95
DeepSS	[30]	2018	Donor			95
SpliceRover	[31]	2018	Acceptor	91	97	95
SpliceRover	[31]	2018	Donor	90	96	96
Splice2Deep	[32]	2020	Acceptor	98	95	97
Splice2Deep	[32]	2020	Donor	99	96	97

ISSN: 1479-7364