Table 1 Summary of conserved elements in human FOXC1 and zebrafish foxc1a/b genomic regions
Conserved element | Human coordinates (hg38) | Corresponding ENCODE cCREs* | Zebrafish coordinates (GRCzZ11) | Length of alignment (bp) | % of identity | Distance to next human gene | Distance to next zebrafish gene |
|---|---|---|---|---|---|---|---|
CEU1 | chr6:1387821–1387980 | EH38E2439030 (chr6:1387819–1388167) | CEU1a chr2:716946–717020 | 78 | 78 | 1.57 Kb upstream of FOXF2 | 519 bp upstream of foxf2a |
CEU1b chr20:26689284–26689441 | 160 | 69 | 565 bp upstream of foxf2b | ||||
CED1 | chr6:1616932–1617028 | EH38E2439207 (chr6:1616739–1617072) | chr2:684320–684414 | 99 | 76 | 2.9 Kb downstream of FOXC1 | 2.5 Kb downstream of foxc1a |
CED2 | chr6:1778296–1778362 | EH38E2439358 (chr6:1777933–1778281) | chr2:577491–577557 | 67 | 84 | 164.4 Kb downstream of FOXC1 | 109.3 Kb downstream of foxc1a |
CED3 | chr6:1903895–1904034 | EH38E2439473 (chr6:1903759–1904109) | chr2:535659–535798 | 140 | 81 | 290 Kb downstream of FOXC1 | 151 Kb downstream of foxc1a |