Table 2 Clinical manifestations and outcomes in each RAA case

Total

20

16

15

8

8

7

3

3

2

2

2

2

1

1

90

Advanced maternal age

3

8

6

5

5

3

1

1

1

1

1

35

High-risk for serum prenatal screening

9

6

3

2

1

2

1

1

1

26

RAA-Positive in NIPS

10

9

7

2

5

4

2

1

1

1

42

Ultrasound abnormalities

8

8

9

4

1

1

1

1

2

1

1

2

1

40

Soft markers

Increased NT (≥ 3.0 mm)

4

1

1

1

1

1

9

Persistent left superior vena cava

1

3

1

1

6

Mild fetal ventriculomegaly (between 10 and 15 mm)

1

1

1

1

4

Single umbilical artery

1

1

1

3

Short fetal femur length

1

1

1

3

Echogenic fetal bowel

1

1

2

Echogenic intracardiac focus

1

1

Enlarged cisterna magna

1

1

Renal echo enhancement

1

1

Absent gallbladder

1

1

Structural defects

Cardiovascular

4

1

3

1

1

1

1

1

1

14

Musculoskeletal

4

1

1

1

7

Diaphragmatic hernia

1

1

2

Urogenital

1

1

Respiratory

1

1

Intrauterine growth retardation

1

2

1

1

5

Pregnancy outcomes

TOP

16

8

14

5

6

4

2

2

2

2

1

1

63

Live birth

4

8

1

3

2

3

1

1

2

1

1

27

Premature delivery

1

2

2

1

6

Postnatal anomaly

2

1

1

2

1

1

8