Table 1 Baseline characteristics of healthy volunteers whose miRNA levels were quantified
| Â | Total | Group classified by AXA3h | Group classified by AUC0-t | ||||||
|---|---|---|---|---|---|---|---|---|---|
Overall | Case | Control | p value | Overall | Case | Control | p value | ||
10Â mg | |||||||||
 n | 26 | 20 | 10 | 10 | 1.000 | 20 | 10 | 10 | 1.000 |
 Male | 15 (57.69%) | 11 (55.00%) | 4 (40.00%) | 7 (70.00%) | 0.370 | 12 (60.00%) | 8 (80.00%) | 4 (40.00%) | 0.170 |
 Fed | 13 (50.00%) | 10 (50.00%) | 5 (50.00%) | 5 (50.00%) | 1.000 | 10 (50.00%) | 5 (50.00%) | 5 (50.00%) | 1.000 |
 Age | 32 (13) | 34 (16) | 37.5 (16) | 31.5 (14) | 0.579 | 35.5 (15) | 33 (14) | 36 (14) | 0.796 |
 BMI | 23.35 (1.8) | 23.35 (1.70) | 23.40 (2.50) | 22.60 (1.60) | 0.853 | 23.40 (2.00) | 23.10 (2.10) | 23.40 (1.80) | 0.912 |
 AXA3h | 134.04 (70.98) | 134.58 (123.28) | 195.93 (74.51) | 86.28 (32.26) | 0.000* | 117.08 (78.49) | 92.95 (35.58) | 167.41 (64.05) | 0.000* |
 C3 | 163.1745 (108.41) | 160.95 (104.41) | 197.43 (85.37) | 103.34 (45.57) | 0.000* | 146.36 (99.96) | 103.34 (42.82) | 194.46 (62.13) | 0.000* |
 Cmax | 191.9635 (69.81) | 188.00 (96.67) | 225.14 (78.56) | 137.44 (78.92) | 0.003* | 187.16 (82.93) | 137.44 (67.60) | 215.98 (57.62) | 0.001* |
 AUC0-t | 1302.5875 (751.46) | 1231.48 (780.15) | 1633.65 (622.65) | 910.76 (415.46) | 0.000* | 1350.74 (866.89) | 840.75 (354.44) | 1702.33 (316.65) | 0.000* |
15Â mg | |||||||||
 n | 39 | 28 | 14 | 14 | 1.000 | 28 | 14 | 14 | 1.000 |
 Male | 33 (84.62%) | 23 (82.14%) | 10 (71.43%) | 13 (92.86%) | 0.326 | 23 (82.14%) | 13 (92.86%) | 10 (71.43%) | 0.326 |
 Fed | 21 (53.85%) | 14 (50.00%) | 7 (50.00%) | 7 (50.00%) | 1.000 | 14 (50.00%) | 7 (50.00%) | 7 (50.00%) | 1.000 |
 Age | 29 (10) | 27 (11) | 24 (8) | 30 (11) | 0.114 | 25 (9) | 27 (10) | 24.5 (9) | 0.401 |
 BMI | 22.2 (3.2) | 22.10 (2.70) | 21.70 (2.30) | 23.20 (2.90) | 0.401 | 23.10 (3.30) | 23.30 (3.50) | 22.55 (3.40) | 0.804 |
 AXA3h | 171.22 (175.59) | 164.39 (219.13) | 273.28 (79.31) | 54.78 (113.13) | 0.000* | 169.96 (155.77) | 93.07 (109.99) | 221.93 (75.05) | 0.000* |
 C3 | 208 (183) | 210.00 (224.25) | 329.50 (75.75) | 107.00 (75.75) | 0.000* | 203.00 (169.50) | 129.00 (99.00) | 277.00 (100.75) | 0.000* |
 Cmax | 283 (164) | 284.00 (172.75) | 358.50 (53.75) | 196.00 (78.75) | 0.000* | 283.00 (136.25) | 201.50 (86.25) | 326.00 (86.50) | 0.000* |
 AUC0-t | 1782.71 (1212.23) | 1816.22 (1123.77) | 2118.18 (542.33) | 1090.19 (491.24) | 0.000* | 1728.31 (1402.69) | 1074.30 (468.58) | 2440.31 (653.37) | 0.000* |