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Fig. 3 | Human Genomics

Fig. 3

From: Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo

Fig. 3

Active regulons in preosteoblast-S1. A GSEA analysis results in target genes of active regulons in preosteoblast-S1, “osteoblast differentiation” term. B GSEA analysis results in target genes of active regulons in preosteoblast-S1, terms of inflammatory response. C Network visualization of active regulons in preosteoblast-S1. Large green dots represent TF, small red dots represent immunity-related target genes, small blue dots represent cell proliferation/differentiation-related target genes, small yellow dots represent both immunity and cell proliferation/differentiation-related target genes; other target genes are shown as gray diamonds. D Violin plots showing average expression levels of gene members related to immunity and cell proliferation/differentiation. Dot size represents pseudotime for each cell from early (small) to late (large). *Adjusted p value < 0.05 (Kruskal–Wallis test)

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Human Genomics

ISSN: 1479-7364