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Fig. 6 | Human Genomics

Fig. 6

From: Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo

Fig. 6

PPI analysis of immunity and cell proliferation/differentiation-related target genes. A PPI network of immunity-related target genes. Dot size represents connection degrees from small (low) to large (high). Red nodes have the higher gene expression ratio of pre-osteoblast S1 in comparison with mature osteoblast. Edge width represents the combinded scores. B PPI network of cell proliferation/differentiation-related target genes. Dot size represents connection degrees from small (low) to large (high). Blue nodes have the higher gene expression ratio of pre-osteoblast S1 in comparison with mature osteoblast. Edge width represents the combinded scores. C Subnetwork in immunity-related PPI network screened by MCODE, MCODE score = 0.94. D Subnetwork in cell proliferation/differentiation-related PPI network screened by MCODE, MCODE score = 0.54 (left) and 0.47 (right). Dot color represents connection degrees in each subnetwork from blue (low) to red (high). Edge width represents the combined scores

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Human Genomics

ISSN: 1479-7364