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Fig. 2 | Human Genomics

Fig. 2

From: Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex

Fig. 2

Effects of rapamycin on social behaviors in Tsc1+/−, Tsc2+/−, and TscD+/− mice. A–C Effects of rapamycin and vehicle on the time spent in active interaction in the social interaction test (A), time spent exploring a familiar mouse (S1) and stranger mouse (S2) in the social novelty session of the three-chambered sociability test (B), and time spent exploring a stranger mouse (S3) and cagemate (C) in the social preference session of the three-chambered sociability test (C). *p < 0.05; **p < 0.01; ***p < 0.001, unpaired t-test (A) and paired t-test (B, C). Each bar indicates the mean ± SEM. Veh vehicle, Rap rapamycin

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Human Genomics

ISSN: 1479-7364