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Fig. 5 | Human Genomics

Fig. 5

From: Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex

Fig. 5

Signaling pathway associated with DETs in Tsc1+/−, Tsc2+/−, and TscD+/− mice with rapamycin treatment. Arrows indicate directional edges, with main actions shown in green. All pathways are commonly initiated from PDLIM2 to STAT3 via STAT4, IRF1, IFNγ, and IRF in Tsc1+/−, Tsc2+/−, and TscD+/− mice (symbol definitions can be found at https://portal.genego.com/legends/MetaCoreQuickReferenceGuide.pdf; accessed July 14, 2022)

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Human Genomics

ISSN: 1479-7364