Fig. 8

Molecular networks of the 56 risk proteins mapped with the 109 risk variant-disease associations. The red nodes represent COVID-19 risk proteins. The gray nodes represent human proteins that interact with risk proteins. A Twenty-four connected networks. Each connected network has at least one interaction with another protein. Networks 1 to 3 contain more than one risk protein, and Networks 4 to 22 are isolated networks has one risk protein. B Seven orphan risk proteins did not have any protein interaction with other human proteins. The dashed lines link risk variants with linked networks. The different colors of squares illustrate the disease mapping based on the risk variant-disease mapping and the similarity of the molecular functions between the constructed networks