Fig. 2

Main features of the pediatric cohort of the study. Distribution of patients according to clinical suspicion and age at recruitment. Data are shown as a violin plot: purple dots represent female subjects while blue diamonds represent male patients. Median and quartiles are shown (a). Distribution of patients according to clinical suspicion and ethnicity. The majority of patients are of Caucasian origin, with only a minority of patients being of African origin, Asian, Latin-American or of mixed origin (b). Distribution of patients divided on the basis of the main disease macro-categories, according to gender (inner circle) and family history (outer circle) (c). Detailed description of the primary disease affecting the pediatric cohort analyzed. Inner circle represents the main macro-categories while the outer circle refers to primary diseases within each macro-category. Numbers in brackets indicate the number of patients (d) CAK: congenital abnormalities of kidney and urinary tract (CAKUT); CIL: ciliopathies; GLO: glomerulopathies; NEP: nephrolithiasis; TUB: tubulopathies; OTH: others; HUS: Hemolytic uremic syndrome; FSGS: focal segmental glomerulosclerosis.