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Fig. 6 | Human Genomics

Fig. 6

From: Integrated analysis of RNA methylation regulators crosstalk and immune infiltration for predictive and personalized therapy of diabetic nephropathy

Fig. 6

Construction of differential expression of methylation gene signatures and functional annotation. A 28 RNA methylation-related differentially expressed genes (DEGs) between three subtypes were shown in the Venn diagram. B Functional annotation for RNA methylation-related genes using GO enrichment analysis. C LASSO coefficient profiles of 52 RNA methylation regulatory genes to verifying the optimal Lambda. D Ten coefficients were selected in the LASSO regression. E The risk score distribution of training set in control and diabetic nephropathy samples. F The validation of risk score distribution of testing set in control and diabetic nephropathy samples. G Distribution of risk score among distinct RNA modification subtypes. H The risk score profiles for each patient and divided into high- and low-risk group according the median cut-off value (17.961)

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Human Genomics

ISSN: 1479-7364