Table 2 Association of PRKCD rs74437127 and CARD9 rs3812555 with VKH diseases
Gene | SNPs | Genotype allele | VKH n (%) | Control n (%) | P value | Pc value | OR(95% CI) |
|---|---|---|---|---|---|---|---|
PRKCD | rs74437127 | TT | 0 (0.000) | 7 (0.008) | 0.007* | NS | – |
TC | 73 (0.080) | 97 (0.111) | 0.026 | NS | 0.698 (0.507–0.960) | ||
CC | 839 (0.920) | 771 (0.881) | 0.006 | NS | 1.550 (1.132–2.124) | ||
T | 73 (0.040) | 111 (0.063) | 0.001 | 0.020 | 0.616 (0.455–0.833) | ||
C | 1751 (0.960) | 1639 (0.937) | 0.001 | 0.020 | 1.624 (1.200–2.199) | ||
CARD9 | rs3812555 | CC | 695 (0.840) | 602 (0.744) | 1.57 × 10–6 | 2.04 × 10–5 | 1.810 (1.418–2.311) |
TC | 119 (0.144) | 187 (0.231) | 6.04 × 10–6 | 7.85 × 10–5 | 0.559 (0.434–0.721) | ||
TT | 13 (0.016) | 20 (0.025) | 0.221* | NS | 0.630 (0.311–1.275) | ||
C | 1509 (0.912) | 1391 (0.860) | 2.12 × 10–6 | 2.76 × 10–5 | 1.698 (1.362–2.118) | ||
T | 145 (0.088) | 227 (0.140) | 2.12 × 10–6 | 2.76 × 10–5 | 0.589 (0.472–0.734) |