Table 1 National allele frequencies of CYP2C9*2 and *3

Europe

South Europe

Bosnia and Herzegovina

81

9.0

-

Croatia

200

16.5

9.5

Greece

283

12.9

8.1

Italy

792

12.4

9.4

Portugal

135

13.2

8.0

Serbia

716

12.3

7.9

Spain

596

13.8

10.1

Turkey

584

10.5

9.8

North Europe

Denmark

276

12.1

5.3

Estonia

2411

8.4

7.2

Finland

12,665

11.4

6.3

Norway

309

9.9

6.5

Sweden

13,495

11.7

6.5

Central and East Europe

Bulgaria

1503

12.5

7.5

Czech

341

11.6

5.9

Germany

118

14.0

5.0

Hungary

535

12.5

8.8

North Macedonia

308

12.4

7.1

Poland

85

-

4.7

Romania

332

11.3

9.3

Russia

290

10.5

6.7

Slovak

112

10.0

8.0

Slovenia

129

12.2

6.3

West Europe

Belgium

121

10.0

7.4

France

151

15.0

8.0

Netherlands

1252

13.0

6.0

UK

397

10.2

5.7

Africa

Benin

111

0.0

0.0

Egypt

247

12.0

6.0

Ethiopia

239

3.3

3.2

Gambia

179

0.4

0.0

Ghana

204

0.0

0.0

Morocco

290

9.5

-

Mozambique

103

0.0

1.0

Nigeria

293

0.0

0.0

Sudan

383

5.0

0.0

Middle East

Iran

693

18.1

6.5

Israel

438

14.3

8.2

Jordan

263

13.5

6.8

Kuwait

108

14.0

5.0

Lebanon

176

15.4

7.8

Oman

641

7.2

3.5

Saudi Arabia

323

12.4

6.3

United Arab Emirates

160

7.2

21.3

Asia

Southeast Asia

Cambodia

122

-

6.6

Indonesia

412

0.0

2.4

Malay

565

1.0

2.9

Thai

1205

0.1

5.3

Vietnam

381

0.0

3.0

East Asia

Bhutan

443

0.3

0.0

China

894

0.1

3.5

Japan

2105

0.0

2.4

Korea

574

0.0

1.1

South Asia

Bangladesh

144

1.7

11.6

India

2435

4.5

9.7

Pakistan

1762

5.0

11.9

South America

Argentina

101

2.6

3.0

Bolivia

778

4.8

3.0

Brazil

721

10.7

6.0

Chile

279

9.0

4.0

Columbia

375

9.3

6.8

Ecuador

297

0.5

3.7

Peru

340

3.8

4.4

Uruguay

103

13.0

7.6

Venezuela

680

7.4

2.3

North America

Costa Rica

443

4.7

2.8

Cuba

128

6.0

9.0

Mexico

1378

3.7

2.8

USA

1411

9.0

4.4

Oceania

Australia

5408

12.8

6.9