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Table 1 Basic characteristics of SNP research objects

From: Association of APP gene polymorphisms and promoter methylation with essential hypertension in Guizhou: a case–control study

Nations

Group

Gender (male/female)

Age (years)

Normal BMI [n (%)]a

Low BMI [n (%)]b

Overweight [n (%)]b

Obesity [n (%)]b

Total populations

Control (n = 335)

151/184

51.93 ± 13.91

176 (52.5)

17 (5.1)

105 (31.3)

37 (11.0)

EH (n = 343)

164/179

58.87 ± 12.85

156 (45.5)

14 (4.1)

123 (35.9)

50 (14.6)

t/χ2

0.511

− 6.744

 

0.038

2.619

3.031

P

0.475

< 0.001

 

0.845

0.106

0.082

Miao population

Control (n = 111)

44/67

51.15 ± 15.92

55 (49.5)

5 (4.5)

39 (35.1)

12 (10.8)

EH (n = 110)

58/52

57.91 ± 13.69

48 (43.6)

3 (2.7)

42 (38.2)

17 (15.5)

t/χ2

3.808

− 3.381

 

0.248

0.500

1.308

P

0.051

0.001

 

0.724

0.479

0.253

Buyi population

Control (n = 117)

52/65

51.63 ± 13.99

65 (55.6)

8 (6.8)

33 (28.2)

11 (9.4)

EH (n = 119)

61/58

60.93 ± 12.91

58 (48.7)

8 (6.7)

41 (34.5)

12 (10.1)

t/χ2

1.098

− 5.308

 

0.046

1.258

0.196

P

0.295

< 0.001

 

0.830

0.262

0.658

Han population

Control (n = 107)

55/52

53.07 ± 11.40

56 (52.3)

4 (3.7)

33 (30.8)

14 (13.1)

EH (n = 114)

45/69

57.63 ± 11.74

50 (43.9)

3 (2.6)

40 (35.1)

21 (18.4)

t/χ2

3.17

− 2.925

 

0.049

1.005

1.733

P

0.075

0.004

 

1.000

0.316

0.188

  1. Bold indicates P < 0.05
  2. Measurement data are expressed as mean ± SD, and Student’s t test is used for comparison between groups. Counting data are expressed as frequency (rate), and Chi-square test is used for comparison between groups
  3. aBMI = kg/m2, Low BMI: BMI < 18.5, Normal BMI: 18.5 ≤ BMI < 24.0, Overweight: 24.0 ≤ BMI < 28.0, Obesity: BMI ≥ 28.0
  4. bCompared with the normal BMI group