Skip to main content

Table 5 Haplotype association analysis between EH group and control group in Guizhou population

From: Association of APP gene polymorphisms and promoter methylation with essential hypertension in Guizhou: a case–control study

Nation

Haplotype

EH group [n (%)] c

Control group [n (%)]

Χ2

OR (95% CI)

Pd

Total populations

ACa

94 (13.7)

93 (13.8)

0.005

0.989 (0.726–1.347)

0.943

GCa

66 (9.6)

72 (10.8)

0.506

0.880 (0.619–1.251)

0.477

TCCb

93 (13.5)

66 (9.9)

4.348

1.427 (1.020–1.996)

0.037

Miao population

ACa

38 (17.1)

18 (8.1)

8.071

2.330 (1.284–4.226)

0.004

GCa

21 (9.7)

35 (15.7)

3.608

0.576 (0.324–1.023)

0.057

TCCb

32 (14.5)

25 (11.1)

1.300

1.386 (0.789–2.435)

0.254

Buyi population

ACa

24 (10.1)

36 (15.6)

3.185

0.608 (0.351–1.054)

0.074

GCa

26 (10.9)

13 (5.8)

4.053

1.997 (1.008–3.956)

0.044

TCCb

24 (10.0)

16 (6.7)

1.594

1.530 (0.788–2.970)

0.207

Han population

ACa

32 (13.9)

38 (17.9)

1.352

0.738 (0.442–1.233)

0.245

GCa

19 (8.5)

24 (11.1)

0.826

0.747 (0.397–1.404)

0.363

TCCb

37 (16.2)

25 (11.9)

1.368

1.383 (0.802–2.385)

0.242

  1. Bold indicates P < 0.05
  2. aHaplotype SNP combination rs2040273–rs2211772
  3. bHaplotype SNP combination rs364051–rs438031–rs463946
  4. cAll those frequency < 0.03 will be ignored in analysis
  5. dThe P value of Fisher exact tests