Fig. 3From: Computational and mitochondrial functional studies of novel compound heterozygous variants in SPATA5 gene support a causal link with epileptogenic encephalopathyMonocyte mitochondrial mass. A Representative confocal image showing mitochondria (green) and nuclei (blue) stained with MitoTracker Green and DAPI, respectively. The regions of interest containing the mitochondria analyzed are marked in yellow. B Quantity of mitochondria per monocyte in case (SPATA5) compared to a healthy control (Control). C Total mitochondrial volume per monocyte in case (SPATA5) compared to a healthy control. D Mitochondrial total surface per monocyte in case (SPATA5) compared to a healthy control. (Unpaired t tests were performed, ***p < 0.001, ****p < 0.0001 (n = 15–27)Back to article page