Table 3 The relationship between adjusted metabolites and metabolic genes in the same metabolic pathway
Features | Metabolic pathway | Associated genes |
|---|---|---|
Hippurate | Metabolism of amino acids | QDPR/FAH/PAOX/MPST/SLC7A5 |
3-phosphoglycerate | Metabolism of carbohydrates | ST3GAL2/PFKP/HS3ST1/HPSE/PGM1 |
C14:0 CE | Metabolism of lipids | AGPS/SGPP1/SQLE/EPHX2 |
C18:0 LPE | Metabolism of lipids | PTGS1/CHPT1/SC5D/PLA2G3/DHCR24 |
6-phosphogluconate | Metabolism of carbohydrates | B4GALT2/PFKFB2/PPP1R3C/SLC25A13/IDUA |
C36:1 PC | Metabolism of lipids | CYP51A1/CERS6/PTGS1/PLA2G3/CERS4/SQLE |
Glutathione reduced | Metabolism of amino acids | MRI1/FAH/GAMT/PAOX/CHDH/CDO1 |
Sarcosine | Metabolism of amino acids | ALDH4A1/GPT2/AGMAT/ASL/AADAT/MPST |