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Fig. 1 | Human Genomics

Fig. 1

From: Integrative analysis of a novel super-enhancer-associated lncRNA prognostic signature and identifying LINC00945 in aggravating glioma progression

Fig. 1

Identification of 6 SE-lncRNAs. A A volcano plot of 2441 differentially expressed SE-genes. B The heatmap shows expression levels of 1688 SE-genes which are highly expressed in GSCs. C Identification of 58 SE-lncRNAs. D The 3494 specific SE-genes were expressed in more than 10% of the 43 glioma patients. E Select each patient's top 100 genes in ChIP-seq, resulting in 1244 SE-genes. F GO and KEGG analyses of the 3494 SE-genes screened by frequency. G GO and KEGG analyses of the 1244 SE-genes screened by rank order. H 8 SE-lncRNAs were obtained by the intersection of 58 SE-lncRNAs with SE-genes obtained by frequency and ranking. I 6 SE-lncRNAs were finally screened by combining the RNA-seq data of TCGA and CGGA databases

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Human Genomics

ISSN: 1479-7364