Table 2 Differentially methylated regions (DMRs) with fold change values above 3.5 after comparing individuals with MDS who progressed to AML against individuals with MDS who did not
Chromosome | Start | End | Fold Change | Genomic loci description | Genomic annotation |
|---|---|---|---|---|---|
chr6 | 169,966,466 | 169,968,275 | 9.52 | CpG-island | CpG43837 |
chr1 | 247,170,879 | 247,172,787 | 5.79 | CpG-island | CpG4368 |
chr1 | 247,170,879 | 247,172,787 | 5.79 | TSS | ZNF124 |
chr1 | 247,170,879 | 247,172,787 | 5.79 | postTSS1KB-TES | ZNF124 |
chr4 | 186,433,489 | 186,435,606 | 5.27 | postTSS1KB-TES | F11-AS1 |
chr4 | 186,433,489 | 186,435,606 | 5.27 | postTSS1KB-TES | RP11-215A19.2 |
chr10 | 133,292,034 | 133,292,157 | 5.04 | CpG-island | CpG6468 |
chr10 | 133,292,034 | 133,292,157 | 5.04 | postTSS1KB-TES | TUBGCP2 |
chr1 | 247,126,037 | 247,127,603 | 4.89 | CpG-island | CpG4367 |
chr1 | 247,126,037 | 247,127,603 | 4.89 | postTSS1KB-TES | ZNF124 |
chr10 | 75,405,211 | 75,405,359 | 3.73 | CpG-island | CpG5460 |
chr10 | 75,405,211 | 75,405,359 | 3.73 | postTSS1KB-TES | ZNF503-AS2 |