Fig. 1

Overview of the analytic pipeline. We refer to Model 1 as the ‘main model’ throughout this paper and focus primarily on significant findings from this model. The other models are referred to as ‘adjusted models’ and treated as sensitivity analyses. Abbreviations used in the figure: CpG = cytosine-phosphate-guanine; ART = assisted reproductive technologies; mat = maternal; BMI = body mass index; BW = birthweight; GA = gestational age; XWAS = X-chromosome-wide association study; DMR = differentially methylated region; FDR = false discovery rate; MoBa = The Mother, Father, and Child Cohort Study; and CHART = The ‘Clinical review of the Health of adults conceived following Assisted Reproductive Technologies’ study