Fig. 1
From: Twist exome capture allows for lower average sequence coverage in clinical exome sequencing
Comparison of exome kits and sequencing platforms. A Ratio of coding regions covered at ≥ 20× for different enrichment and sequencing platforms for RefSeq and Ensembl. B Boxplots of evenness scores for different enrichment kits and sequencing platforms. C Ratio of coding regions covered at ≥ 20× for different enrichment platforms when down-sampled to 50×. D GC content of insufficiently and sufficiently covered targets is significantly different for all kits and platforms (Mann–Whitney U-Test p value < 0.001)