Twist exome capture allows for lower average sequence coverage in clinical exome sequencing

Table 1 Overview of samples used in this study

Enrichment/library	Average coverage	Coverage range (min–max)	Number of samples
Agilent V5	274.8	163.8–345.4	20
Agilent V7	239.6	131.1–370.6	20
Twist	139.2	119.7–158.5	20
WGS	59.3	50.86–69.33	20
LRS	29.4	24.24–38.86	18

Columns depict (from left to the right) the exome kits and the platforms; the average coverage across the target regions of the enrichment kits for the exomes; the range of coverage; the number of samples used in the analysis

ISSN: 1479-7364