Fig. 2

The positive association between hsa-miR-143-3p and neutrophil count is mediated by BCL2 expression. A Numerous miRNAs are associated with neutrophil count, including hsa-miR-143-3p (labeled). Both miRNA expression and blood phenotype levels were measured from the same blood sample, collected at the time of hospital admission. miRNAs significant at p < 0.05 are highlighted in blue. miRNAs significant at p < 0.01 are highlighted in red. Both miRNA expression and blood phenotype levels were standardized. B Correlation between hsa-miR-143-3p expression (x-axis) and BCL2 transcript expression (y-axis). C Correlation between BCL2 transcript expression (x-axis) and absolute neutrophil count (y-axis). The Pearson correlation and p value are in blue. miRNA expression, transcript expression and neutrophil count have all been standardized