Table 4 Article details about genes associated with heart failure (HF)

32111823

3

GWAS:

HF = 24,829

Controls = 1,614,513

European

Ischemic heart disease: myocardial infarction, percutaneous coronary intervention or coronary artery bypass graft surgery; HF

P < 5E−8

RNA-seq

Mendelian randomization (MR Egger), linear regression

29717556

1

HF = 3

St. Louis (USA), Ghent (Belgium)

Bilateral inguinal hernia correction; retropatellar cartilage problems, verapamil for symptomatic ventricular extrasystoles

N/A

N/A

Echocardiography

34327238

1

GWAS:

HF = 191

Asian, American, African, European

Cancer patients who received adjuvant doxorubicin therapy

P = 5.63E−5, P = 5.70E−5

N/A

GraphPad Prism, Linear Regression model

31919418

14

GWAS:

HF = 47,309

Controls = 930,014

European

HF

p < 5E−8

RNA-seq

Two-sample MR, Mendelian randomization (MG Egger)

29457789

1

HF = 1,659

European, African-American

Cardiomyopathy patients with implantable cardioverter defibrillators (ICDs)

p < 5E−2

RNA-seq (by Illumina truSEq and Nugen Ovation)

GraphPad, Fisher's exact test, ANOVA

31554410

8

GWAS:

HF = 16,923

European

Myocardial infarction or HF

1.50E−05

N/A

LDPred tool (used to obtain PRS), CMR protocol and analysis methods