Table 2 Distribution of genotypes and allele frequencies
Gene | SNP | Genotype | n (%) | Allele | n (%) | Hardy–Weinberg equilibrium, p value |
|---|---|---|---|---|---|---|
ABCB1 | rs1045642 | AA | 15 (15.8) | A | 80 (42.1) | 0.438 |
AG | 50 (52.6) | G | 110 (57.9) | |||
GG | 30 (31.6) | |||||
rs1128503 | AA | 35 (36.8) | A | 120 (63.2) | 0.202 | |
AG | 50 (52.6) | G | 70 (36.8) | |||
GG | 10 (10.5) | |||||
rs4148738 | CC | 15 (15.8) | C | 81 (42.6) | 0.342 | |
CT | 51 (53.7) | T | 109 (57.4) | |||
TT | 29 (30.5) | |||||
rs4728709 | GG | 66 (72.5) | G | 155 (85.2) | 0.998 | |
GA | 23 (25.3) | A | 27 (14.8) | |||
AA | 2 (2.2) | |||||
CYP3A4 | rs2242480 | CC | 39 (42.8) | C | 123 (67.6) | 0.220 |
CT | 45 (49.4) | T | 59 (32.4) | |||
TT | 7 (7.7) | |||||
rs4646437 | GG | 60 (65.9) | G | 148 (813) | 0.903 | |
AG | 28 (30.8) | A | 34 (18.7) | |||
AA | 3 (3.3) | |||||
CYP3A5 | rs776746 | TT | 7 (8.0) | T | 54 (30.7) | 0.520 |
TC | 40 (45.4) | C | 122 (69.3) | |||
CC | 41 (46.6) | |||||
ABCG2 | rs2231137 | CC | 42 (46.2) | C | 125 (68.7) | 0.652 |
TC | 41 (45.0) | T | 57 (31.3) | |||
TT | 8 (8.8) | |||||
rs2231142 | GG | 45 (49.4) | G | 127 (69.8) | 0.732 | |
GT | 37 (40.6) | T | 55 (30.2) | |||
TT | 9 (9.9) |