Table 3 Comparison of the rivaroxaban Ctrough/D among genotypes
SNP | Genotype | Ctrough/D | P |
|---|---|---|---|
ABCB1 rs1045642 (A > G) | AA | 1.34 (0.66,3.25) | 0.072 |
AG | 0.89 (0.37,1.88) | ||
GG | 0.71 (0.34,1.11) | ||
ABCB1 rs1128503 (A > G) | AA | 0.92 (0.51,2.17) | 0.082 |
AG | 0.97 (0.39,1.70) | ||
GG | 0.39 (0.21,1.00) | ||
ABCB1 rs4148738 (C > T) | CC | 1.22 (0.66,3.47) | 0.039* |
CT | 0.88 (0.38,1.84) | ||
TT | 0.66 (0.31,1.20) | ||
ABCB1 rs4728709 (G > A) | GG | 1.06 (0.50,1.81) | 0.008* |
GA | 0.40 (0.30,0.88) | ||
AA | |||
CYP3A4 rs2242480(C > T) | CC | 0.96 (0.42,1.98) | 0.505 |
CT | 0.71 (0.29,1.60) | ||
TT | 1.10 (0.63,2.19) | ||
CYP3A4 rs4646437(G > A) | GG | 0.81 (0.40,1.55) | 0.591 |
GA | 0.81 (0.26,1.71) | ||
AA | 1.10 (1.03,-) | ||
CYP3A5 rs776746(T > C) | TT | 1.10 (0.63,2.19) | 0.395 |
TC | 1.01 (0.50,1.73) | ||
CC | 0.66 (0.36,1.51) | ||
ABCG2 rs2231137(C > T) | CC | 0.78 (0.35,1.55) | 0.419 |
CT | 1.00 (0.40,2.00) | ||
TT | 0.66 (0.21,1.33) | ||
ABCG2 rs2231142(G > T) | GG | 0.92 (0.36,1.55) | 0.976 |
GT | 0.88 (0.43,1.78) | ||
TT | 0.83 (0.34,2.26) |