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Fig. 2 | Human Genomics

Fig. 2

From: CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes

Fig. 2

Analysis of protein and non-coding genes associated with rSNPs. A For each GWAS (row) a stacked bar plot shows the number of associated genes per category. B Dot plot visualizing per GWAS how many regulatory elements (REMs) and rSNPs are associated with a gene. Genes are separated into protein-coding, protein-coding associated with the disease according to DisGeNET, non-coding, and experimentally studied non-coding genes in this work (circle colour). The x-axis shows the number of REMs for a gene overlapping with at least one rSNP and the y-axis the number of rSNPs for all REMs associated with a gene. The size of the dot correlates with the number of genes having the same x- and y- coordinate values

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