Fig. 2From: A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritisLocal genetic correlation: BMI-adjusted sex hormone-binding globulin and rheumatoid arthritis (excluding MHC). X-axis represents chromosomes, Y-axis represents negative logarithm of P values, and each dot in the Manhattan plot represents a linkage-disequilibrium independent genomic region. Chromosomes and genomic regions for significant local genetic correlations are marked. MHC regions were excluded due to their complex LD pattern. SHBGadjBMI: sex hormone-binding globulin adjusted for BMI; RA: rheumatoid arthritisBack to article page