Fig. 3

Detected AS and DEAS Events in malignant vs. benign prostate samples: Clariom D cohort. a Circle plot shows the count and proportion of detected alternative splicing (AS) events, while c presents the differentially expressed alternative splicing (DEAS) events, broken down by event type. Circle plots b and d represent the number of parent genes implicated in detected AS and DEAS events, respectively, per event type. e UpSet plot elucidates the detected AS event parent genes, indicating the number of genes engaged in distinct event types (illustrated by horizontal bars) and their involvement in various event type combinations (represented by vertical bars and connected red dots). The UpSet plot f does the same for DEAS event parent genes. RI retained intron, A3SS alternative 3′ splice site, A5SS alternative 5′ splice site, CE cassette exon, ME mutually exclusive exons, AFE alternative first exon, ALE alternative last exon