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Fig. 8 | Human Genomics

Fig. 8

From: Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer

Fig. 8

ROC curve comparisons of various model parameters for predicting patient’s 3-, 5-, 8-year BCRFS. Receiver operating characteristic (ROC) curves illustrating 3-, 5-, and 8-year biochemical recurrence-free survival (BCRFS) predictions for patients diagnosed with prostate cancer in The Cancer Genome Atlas Prostate Adenocarcinoma (TCGA-PRAD) training set (a, b, and c, respectively), the testing set (d, e, and f, respectively), and the complete set (g, h, and i, respectively). Different parameters employed are colour-coded and labelled in each subfigure. Age (< 60 vs. ≥ 60): age at diagnosis; Path_T/pathological T stage (T2 vs. T3-T4): tumour stage; Path_N/pathological N stage (N0 vs. N1): lymph node status (N0 = without lymph node metastasis; N1 = with lymph node metastasis); Gleason: Gleason score (≤ 7 vs. > 7)

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