Table 2 Top 10 up-regulated and down-regulated alternative splicing events in the Clariom D dataset
ProbeID | Gene name | Event type | Genomic position | Splicing Z value | Splicing p value | Delta PSI |
|---|---|---|---|---|---|---|
Top10 up-regulated events | ||||||
TC1500008343.hg_3 | UNC45A | Alternative Last Exon | 15:90931052–90933977 | − 5.30043915 | 1.16E−07 | 0.200665185 |
TC0600011184.hg_1 | HIST1H2BJ | Complex Event | 6:27126462–27132525 | − 5.059966554 | 4.19E−07 | 0.152888644 |
TC1700011923.hg_6 | CANT1 | Complex Event | 17:78997774–78998148 | − 4.997983001 | 5.79E−07 | 0.2510289 |
TC0100018146.hg_1 | ZNF692 | Complex Event | 1:248850516–248853937 | − 4.820815714 | 1.43E−06 | 0.106067575 |
TC0100008145.hg_1 | TSPAN1 | Complex Event | 1:46175409–46181100 | − 4.75097649 | 2.02E−06 | 0.258356425 |
TC0400007928.hg_7 | FRAS1 | Cassette Exon | 4:78419063–78424388 | − 4.661850479 | 3.13E−06 | 0.13807046 |
TC1100013040.hg_13 | TM7SF2 | Complex Event | 11:65115394–65115893 | − 4.572538539 | 4.82E−06 | 0.121049901 |
TC0400011721.hg_1 | MAD2L1 | Complex Event | 4:120060977–120066662 | − 4.485818363 | 7.26E−06 | 0.18598516 |
TC1600009200.hg_3 | TRAP1 | Complex Event | 16:3671791–3674339 | − 4.481367645 | 7.42E−06 | 0.126216189 |
TC1100011094.hg_5 | UBXN1 | Complex Event | 11:62678118–62678690 | − 4.429188469 | 9.46E−06 | 0.11029505 |
Top10 down-regulated events | ||||||
TC0600012049.hg_1 | GSTA7P | Retained Intron | 6:52739711–52741583 | 5.016013876 | 5.28E−07 | − 0.138058598 |
TC1600006607.hg_7 | ABCA17P | Complex Event | 16:2404228–2406828 | 4.954495463 | 7.25E−07 | − 0.272021512 |
TC2200008103.hg_1 | YPEL1 | Retained Intron | 22:21701218–21703370 | 4.882892011 | 1.05E−06 | − 0.249262708 |
TC0X00008794.hg_1 | SLC6A8 | Alternative Last Exon | X:153692107–153693041 | 4.723126799 | 2.32E−06 | − 0.216009533 |
TC0900008516.hg_4 | C9orf91 | Retained Intron | 9:114637070–114638544 | 4.644610178 | 3.41E−06 | − 0.201023874 |
TC0400009396.hg_8 | NEIL3 | Retained Intron | 4:177341642–177351380 | 4.641704288 | 3.46E−06 | − 0.272342085 |
TC1700012277.hg_2 | CDK5RAP3 | Complex Event | 17:47974031–47974400 | 4.504297022 | 6.66E−06 | − 0.209587634 |
TC1400008749.hg_5 | RABGGTA | Retained Intron | 14:24266889–24267660 | 4.491051378 | 7.09E−06 | − 0.216635165 |
TC0100010297.hg_16 | NCSTN | Complex Event | 1:160352206–160353160 | 4.434837994 | 9.21E−06 | − 0.231525085 |
TC0800009237.hg_15 | GPAA1 | Alternative 5′ Splice Site | 8:144084040–144084134 | 4.379927673 | 1.19E−05 | − 0.26203504 |