Table 1 Sensitivity analysis of the causal association between type 1 diabetes and PCOS
Exposure | N | Heterogeneity | Pleiotropy | MR-PRESSO | ||
|---|---|---|---|---|---|---|
Q value | P value | Intercept | P value | P value | ||
Type 1 diabetes, wide definition | 36 | 30.17 | 0.70 | − 0.01 | 0.21 | 0.73 |
Type 1 diabetes, early onset | 18 | 22.09 | 0.18 | 0.0002 | 0.99 | 0.25 |
Type 1 diabetes with coma | 12 | 7.28 | 0.78 | − 0.05 | 0.38 | 0.82 |
Type 1 diabetes with ketoacidosis | 11 | 12.37 | 0.26 | − 0.05 | 0.08 | 0.31 |
Type 1 diabetes with neurological complications | 6 | 4.15 | 0.53 | − 0.04 | 0.44 | 0.53 |
Type 1 diabetes with ophthalmic complications | 25 | 28.67 | 0.23 | − 0.02 | 0.24 | 0.25 |
Type 1 diabetes with peripheral circulatory complications | 6 | 8.30 | 0.14 | 0.06 | 0.48 | 0.22 |
Type 1 diabetes with renal complications | 8 | 17.62 | 0.01 | − 0.002 | 0.97 | 0.04 |
Type 1 diabetes with other specified/multiple/unspecified complications | 23 | 32.30 | 32.30 | − 0.02 | 0.31 | 0.06 |