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Table 2 Differentially expressed mRNAs and miRNAs identified in whole cohort and sensitivity analyses

From: A case–control comparison of acute-phase peripheral blood gene expression in participants diagnosed with minor ischaemic stroke or stroke mimics

Gene ID

Gene symbol [family]

Difference between groups (whole cohort analysis)

Difference between groups (sensitivity analysis)

LogFC

LogFC sd

p value

LogFC

LogFC sd

p value

Long RNAs

       

ENSG00000144820

ADGRG7

− 3.08

1.97

3.02E−08

− 3.22

1.96

6.90E−09

ENSG00000211935

IGHV1-3

− 2.26

1.45

5.23E−04

− 2.35

1.42

6.14E−04

ENSG00000211623

IGKV2D-26

− 3.18

2.27

1.76E−03

− 3.23

2.32

6.75E−03

ENSG00000281383

ENSG00000281383

− 1.86

1.46

3.67E−03

− 1.96

1.49

8.02E−03

ENSG00000167306

MYO5B

− 1.09

0.29

1.04E−02

− 1.21

0.27

8.24E−03

ENSG00000280800

ENSG00000280800

− 1.73

1.35

6.73E−03

− 1.82

1.38

9.80E−03

ENSG00000280614

ENSG00000280614

− 1.73

1.35

6.73E−03

− 1.82

1.38

9.80E−03

ENSG00000281181

ENSG00000281181

− 1.73

1.35

6.73E−03

− 1.82

1.38

9.80E−03

ENSG00000223518

ENSG00000223518

− 2.97

2.19

8.26E−03

− 3.06

2.24

1.85E−02

ENSG00000162437

RAVER2

− 0.99

0.34

8.26E−03

− 1.01

0.35

2.59E−02

Micro-RNAs

ENSG00000198974

MIR30E [mir-30]

0.32

0.07

9.00E−04

0.35

0.09

4.36E−05

ENSG00000276830

MIR6730

− 0.52

0.06

1.41E−02

− 0.6

0.08

8.45E−04

ENSG00000284464

MIR1306 [mir-1306]

− 0.38

0.07

1.43E−02

− 0.44

0.09

1.11E−03

ENSG00000265565

MIR3143

0.41

0.08

1.06E−02

0.44

0.09

2.34E−03

ENSG00000283450

MIR486-2 [mir-486]

− 0.43

0.08

1.43E−02

− 0.47

0.09

3.47E−03

ENSG00000276926

MIR6797

− 0.55

0.06

1.43E−02

− 0.6

0.07

3.47E−03

ENSG00000221598

MIR1249 [mir-1249]

− 0.52

0.08

1.68E−02

− 0.56

0.09

5.38E−03

ENSG00000207948

MIR328 [mir-328]

− 0.33

0.07

2.95E−02

− 0.37

0.08

7.56E−03

ENSG00000274705

MIR486-1 [mir-486]

− 0.35

0.08

3.10E−02

− 0.39

0.09

7.62E−03

ENSG00000264610

MIR4685

− 0.39

0.07

1.99E−02

− 0.41

0.08

7.62E−03

ENSG00000275101

MIR6766

− 0.42

0.08

3.59E−02

− 0.48

0.09

7.62E−03

ENSG00000273898

MIR6798

− 0.39

0.09

4.95E−02

− 0.47

0.1

7.62E−03

ENSG00000283935

MIR423 [mir-423]

− 0.33

0.07

1.99E−02

− 0.34

0.08

7.81E−03

ENSG00000207758

MIR532 [mir-188]

− 0.25

0.07

3.61E−02

− 0.28

0.08

7.81E−03

ENSG00000199168

MIR374A [mir-374]

0.6

0.07

2.02E−02

0.66

0.08

8.20E−03

ENSG00000207952

MIR624 [mir-624]

0.55

0.07

1.93E−02

0.57

0.08

1.03E−02

ENSG00000283785

MIR15A [mir-15]

0.53

0.09

4.09E−02

0.58

0.1

1.04E−02

ENSG00000199122

MIR148B [mir-148]

0.21

0.07

4.02E−02

0.23

0.08

1.04E−02

ENSG00000212027

MIR374B [mir-374]

0.49

0.07

4.09E−02

0.54

0.08

1.04E−02

ENSG00000275519

MIR6804

− 0.43

0.07

4.45E−02

− 0.5

0.08

1.05E−02

ENSG00000207698

MIR32 [mir-32]

0.92

0.07

4.42E−02

1.01

0.08

1.34E−02

ENSG00000271886

MIR98 [let-7]

0.5

0.08

2.75E−02

0.49

0.09

1.34E−02

ENSG00000283762

MIR20A [mir-17]

0.55

0.12

4.76E−02

0.59

0.13

1.37E−02

ENSG00000198995

MIR340 [mir-340]

0.27

0.07

4.76E−02

0.29

0.08

1.37E−02

ENSG00000211514

MIR454 [mir-454]

0.32

0.08

4.76E−02

0.33

0.09

1.37E−02

ENSG00000199158

MIR96 [mir-96]

0.56

0.09

4.09E−02

0.59

0.1

1.51E−02

ENSG00000265483

MIR4443

− 0.8

0.19

3.32E−02

− 0.73

0.22

1.87E−02

ENSG00000207864

MIR27B [mir-27]

0.38

0.07

4.76E−02

0.39

0.08

2.22E−02

ENSG00000266297

MIR744 [mir-744]

− 0.26

0.07

4.14E−02

− 0.26

0.08

2.42E−02

ENSG00000264157

MIR3127 [mir-3127]

− 0.3

0.08

4.81E−02

− 0.3

0.09

2.57E−02

  1. miRNA gene family assignment based on miRbase annotation. Log FC: Fold change in transcript expression in participants with strokes, compared to stroke mimics. Std Dev: Standard deviation of fold change. p value refers to false discovery rate corrected ‘P-union’ p value reported by consensusDE. NA not annotated. Annotations in square brackets refer to the miRNA family to which the identified miRNAs belong 
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Human Genomics

ISSN: 1479-7364