Fig. 4
From: Phenome-wide association study on miRNA-related sequence variants: the UK Biobank
Enhanced volcano plots for PheWAS results of SNPs in seed (a), mature (b), or precursor genes (c) of miRNAs. Plots were only created for variants with at least one FDR-significant finding and shown for those with P > 1 × 10–50. Full results with allele information are provided in Additional file 1: Table S2. The X-axis denotes effect estimates (log odds ratio) for corresponding effect alleles. Y axis indicates − log10 of the association p values between each variant and clinical condition. Different colours of the dots represent different variants. Different shapes show different disease groups. Thresholds of significance are indicated by dashed blue (nominal), red (FDR < 0.05), and purple (Bonferroni or P < 0.05/(346 × 905)) lines