Fig. 1
From: SPP1 is associated with adverse prognosis and predicts immunotherapy efficacy in penile cancer
Filtration of genes related to PSCC’s occurrence and lymph node metastasis. A Volcano plot exhibiting significantly differentially expressed genes between PSCC and N. B Volcano plot exhibiting significantly differentially expressed genes between LM and N. C Venn plots revealed 98 intersection genes including 7 upregulated genes in the highly expressed groups and 91 downregulated genes in the lowly expressed groups. D Heatmap showing the expression profiles of 98 overlapping genes in 8 paired tissues of penile cancer patients. GEHIC: genes expressed highly in carcinoma of penis, GEHILNM: genes expressed highly in lymphatic node metastasis, GELIC: genes expressed lowly in carcinoma of penis, GELILNM: genes expressed lowly in lymphatic node metastasis, PSCC: squamous cell carcinoma of the penis, LM: lymphatic metastasis, N: normal tissue