Fig. 8
From: SPP1 is associated with adverse prognosis and predicts immunotherapy efficacy in penile cancer
Potential intrinsic immune response and escape landscapes in the high-SPP1 and low-SPP1 groups. A Comparison of enrichment scores of oncogenic pathways between the high-SPP1 and low-SPP1 groups. B Enrichment plots from gene set enrichment analysis (GSEA) showing differential enrichment of genes in KEGG with high SPP1 expression (including the cGMP-PKG signaling pathway, NF-kappa B signaling pathway, p53 signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, and the TNF signaling pathway showed significant differential enrichment in the high-SPP1 expression phenotype). C Heatmap showing the different GSVA scores of cancer hallmark gene sets between the high-SPP1 group and the low-SPP1 group