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Table 1 Relationship between SPP1 and clinicopathological features in 183 PSCC patients

From: SPP1 is associated with adverse prognosis and predicts immunotherapy efficacy in penile cancer

 

High-SPP1 group (N = 78)

Low-SPP1 group (N = 105)

P-value

Age

 < 55

44 (56.4%)

64 (61.0%)

0.641

 > 55

34 (43.6%)

41 (39.0%)

pT status

pT1

34 (43.6%)

26 (24.8%)

0.026

pT2

12 (15.4%)

17 (16.2%)

pT3

25 (33.3%)

51 (48.6%)

pT4

6 (7.7%)

11 (10.5%)

pN status

pN0

44 (56.4%)

49 (46.7%)

0.274

pN1

9 (11.5%)

12 (11.4%)

pN2

11 (14.1%)

12 (11.4%)

pN3

14 (17.9%)

32 (30.5%)

Metastasis

M0

76 (97.4%)

99 (94.3%)

0.506

M1

2 (2.6%)

6 (5.7%)

Clinical stage

Stage1

24 (30.8%)

22 (21.0%)

0.215

Stage2

21 (26.9%)

24 (22.9%)

Stage3

16 (20.5%)

23 (21.9%)

Stage4

17 (21.8%)

36 (34.3%)

Histology

G1

44 (56.4%)

56 (53.3%)

0.0369

G2

29 (37.2%)

29 (27.6%)

G3

5 (6.4%)

20 (19.0%)

ENE

Negative

67 (85.9%)

79 (75.2%)

0.112

Positive

11 (14.1%)

26 (24.8%)

  1. TNM Staging System and Clinical stage based on the AJCC Cancer Staging Manual for Penile Cancer (8th ed, 2017); PSCC = penile squamous cell carcinoma; ENE = extranodal extension.